How insulin resistance leads to metabolic disorder and how to combat it?

Amazingly, insulin resistance is a hot and burning topic these days.1 in every 4 Americans is suspected to have insulin resistance. Unfortunately, our fast-paced, high-stress and inactive lifestyles bring this condition. Along with this, gut health matters most for the resilience of the digestive system functioning. Any deviation leads to many metabolic disorders. Also, health care is the most fundamental task of human life.

Fortunately, insulin resistance is preventable and even reversible.

Also, every day your body uses a hormone called insulin to turn your meals into energy. Sometimes this process can be interrupted and cause insulin resistance. Consequently, leading to elevated glucose levels and potentially prediabetes or type 2 diabetes.

Below is an overview of intestinal inflammation & insulin resistance.

Know the role of gut microbiota in insulin resistance

 Role of intestinal inflammation as an early event in obesity and insulin resistance

Primarily, obesity-associated systemic and adipose tissue inflammation promotes insulin resistance. It underlies many obesity-linked health risks. Along with this, diet-induced changes in gut microbiota also contribute to obesity. Recent findings support a concept that high-fat diet and bacteria interact to promote early inflammatory changes in the small intestine.

Somehow, obesity has reached pandemic populations affecting millions. Also, it is associated with low-grade systemic inflammations. So, insulin resistance is a condition in which elevated plasma levels maintain normal fasting. Also, it is a key factor in the deleterious effects of obesity. It includes glucose intolerance and an increased risk of non-alcoholic fatty liver disease (NAFLD). However, the diet-induced inflammation in the intestine precedes insulin resistance.

Insulin resistance occurs when excess glucose in the blood reduces the ability of the cells to absorb and use blood sugar for energy.
Thus, if the pancreas can make enough insulin to overcome the low rate of absorption. Then, diabetes is less likely to develop, and blood glucose will stay with. How does insulin resistance cause diabetes?

Prediabetic patient’s pancreas is hard to release insulin. Pancreas ability to release insulin decreases which results in Type-II diabetes.

Development:

Insulin is important to regulate glucose in the bloodstream. Also, it is an important chemical messenger. It instructs the liver to store glucose.

Reasons complex to investigate:
  • Body cells less affected by insulin.
  • Resistance causes the pancreas to secrete less insulin to maintain blood sugar levels.
  • The pancreas is unable to maintain release of extra insulin.
  • High blood glucose develops Type-II diabetes.
Health issues regarding insulin resistance:
  • Acanthosis nigricans: Resultantly, the formation of dark patches on groins, armpits, and one back of the neck.
  • Polycystic ovary syndrome (PCOS):  In most cases, insulin resistance can worsen the symptoms of PCOS. It includes irregular menstrual cycles, infertility, and periods that cause pain.
Risk factors:
  • Obesity
  • Sedentary lifestyle
  • Smoking
  • Sleep issue
  • High Blood Pressure
Other factors that may contribute to insulin resistance:
  • Certain medicines, such as glucocorticoids some antipsychotics, and some medicines for HIV.
  • Hormonal disorders, such as Cushing’s syndrome and acromegaly.
  • Sleep problems, especially sleep apnea.

Further, the U.S. Department of Health and Human Services recommends that all people who are overweight and over 45 years old receive testing for diabetes.

Excess weight and lack of physical activity are major factors to insulin resistance

Thyroid formation:

Insulin resistance increases the incidence of thyroid problems.

High TGD- Low HDL: However, TGs often elevate in tandem with fatty deposits in the liver; a fattier liver does not as effectively produce healthful HDL-cholesterol. The medical term for this condition of high TGs and lower HDL is diabetic atherogenic dyslipidemia.

Diagnosis:

However, they often use the fasting plasma glucose (FPG) test or the A1C test to diagnose prediabetes. The A1C test reflects your average blood glucose over the past 3 months. The FPG and OGTT show your blood glucose level at the time of the test. The A1C test is not as sensitive as the other tests. Generally, often doctors use the OGTT to check for gestational diabetes, a type of diabetes that develops during pregnancy.

  • A1C test: This measures a person’s average blood sugar level over the previous 2–3 months. Preferably in the range of less best

Typical normal 4.8-5.7%

Prediabetes <5.8-6.4

Diabetes >6.4

Optimal level used by many functional practitioners is less or equal to <5.4%

  • Fasting blood glucose test: Also, a doctor checks glucose levels after a person refrains from eating or drinking for 8 or more hours.
  • Random glucose test: This involves a medical professional checking blood glucose levels at some point during the day.
Insulin resistance and PCOS:

Consequently, the more carbs you eat, especially if sugary or processed, the higher the blood sugar rises. However, fat does not cause blood sugar to rise. Furthermore, protein has a minimal effect on raising blood sugar. In addition, elevated blood sugar triggers the pancreas to produce a hormone called insulin.

Treatment and Control:
  • Firstly, have a Low-Carb Diet.
  • Then, avoid All Forms of Sugar and refined carbohydrate
  • After it, add Healthier protein more.
  • Also, include more soluble fibers.
  • Portion control
  • Do, Intermittent fasting
  • Then, hydrate to quench hunger
  • Along with this, exercise Regularly
  • Essentially, lose weight and belly fat
Recipe:
  • I avocado halved and pitted
  • 2 eggs
  • Salt for taste- ½ to 1 tablespoon
  • Bowl for salsa
  • 1 tablespoon cooking olive oil
Assembling salsa:
  • 2 fresh chopped tomatoes
  • 1/3 red onions sliced chopped
  • 1 small chopped jalapeno
  • Juice of 1 lime
  • 1/3 chopped cilantro
  • Salt and pepper to taste
  • Pinch dried oregano
  • Pinch of cayenne
  • Mix well and set aside
Direction:
  1. Firstly, place each avocado on a serving plate.
  2. Secondly, heat the pan. Then, crack one egg at a time and cook as sunny side up or a bit more on your preference how runny you like it. (you may also poach the egg).
  3. Thirdly, place the cooked eggs in the middle of the avocado.
  4. finally, serve the avocado eggs immediately topped with salsa

 

 

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